
Polynucleotide Treatments
IN BELSIZE PARK HAMPSTEAD, NORTH WEST LONDON, MARYLEBONE
Ageing isn’t just about wrinkles or sagging skin - it’s a cellular process that affects the skin’s ability to regenerate, repair, and maintain hydration. Over time, collagen and elastin production slows down, skin becomes thinner, and its ability to retain moisture diminishes. This results in dullness, fine lines, loss of elasticity, and overall skin fatigue.
Unlike fillers that simply add volume, polynucleotides work at a deeper level, stimulating skin repair, improving elasticity, and enhancing overall skin health. At our Belsize Park clinic in North West London, we offer advanced polynucleotide treatments designed to restore vitality, strengthen the skin’s foundation, and support long-term regeneration for a naturally refreshed appearance.

What are Polynucleotides?
Polynucleotides are powerful biostimulators derived from DNA molecules. These natural molecules work by repairing damaged skin cells, boosting collagen production, and improving tissue quality. Unlike fillers, which add volume, polynucleotides focus on rejuvenating the skin from within, making them ideal for skin quality improvement, deep hydration, and long-term regeneration.

This treatment helps to:
IMPROVE SKIN ELASTICITY AND FIRMNESS
STIMULATE COLLAGEN AND FIBROBLAST ACTIVITY FOR LONG-TERM SKIN REPAIR
REDUCE FINE LINES AND CREPEY TEXTURE
IMPROVE SKIN RESILIENCE, MAKING IT STRONGER AND MORE YOUTHFUL
Polynucleotides are also highly effective for under-eye rejuvenation, helping to reduce dark circles, fine lines, and skin thinning in this delicate area. They are also used to strengthen and revitalise the skin on the neck, décolletage, and hands, where skin ageing is often more pronounced.

How Polynucleotides work
Polynucleotides work at a cellular level to improve the skin’s regenerative capacity. When injected into the skin, they stimulate fibroblast activity, which encourages new collagen and elastin production. This results in firmer, more hydrated skin with better texture and elasticity over time.
Unlike other treatments, polynucleotides also have anti-inflammatory properties, helping to repair damaged or stressed skin, making them particularly beneficial for those with sensitive, fragile, or ageing skin.
While immediate hydration and glow can be noticed within days, the real results develop over several weeks as the skin repairs itself from within. The treatment is performed over a series of sessions, with results improving progressively.

What to expect from Polynucleotides
Before treatment, we conduct a thorough consultation to assess your skin concerns and determine the best approach for your needs. Unlike traditional injectables, polynucleotide treatments are designed to work with your skin’s natural repair processes, ensuring long-term benefits rather than just immediate changes.
The procedure itself is quick, taking around 30 minutes. Polynucleotides are injected using a fine needle or cannula, depending on the treatment area. The treatment is minimally invasive with only mild discomfort, and numbing cream can be applied if needed.
Results last around six months, and many patients choose to have maintenance treatments every six months to keep their skin in optimal condition.
There is minimal downtime, with only mild swelling or redness at the injection points, which usually resolves within a few hours.
What to expect from Polynucleotides
Before treatment, we conduct a thorough consultation to assess your skin concerns and determine the best approach for your needs. Unlike traditional injectables, polynucleotide treatments are designed to work with your skin’s natural repair processes, ensuring long-term benefits rather than just immediate changes.
The procedure itself is quick, taking around 30 minutes. Polynucleotides are injected using a fine needle or cannula, depending on the treatment area. The treatment is minimally invasive with only mild discomfort, and numbing cream can be applied if needed.
Results last around six months, and many patients choose to have maintenance treatments every six months to keep their skin in optimal condition.
There is minimal downtime, with only mild swelling or redness at the injection points, which usually resolves within a few hours.
Book a consultation
If you’re considering polynucleotide treatments in North West London or Marylebone, we offer expert-led, personalised skin rejuvenation treatments that focus on deep regeneration, hydration, and long-term skin health. Our approach ensures that your skin not only looks better but also functions at its best, creating stronger, firmer, and more radiant skin over time.
Book a consultation today to discover how polynucleotides can help you achieve healthier, more youthful skin with natural, long-lasting results.


Frequently Asked Questions
Unlike fillers, which add volume to specific areas, polynucleotides work at a cellular level to improve overall skin quality. They stimulate collagen, improve elasticity, and enhance hydration, making the skin look naturally healthier rather than simply plumper.
Most patients experience minimal discomfort, as the injections are very fine. Polynucleotides contain natural hydrating properties that improve skin comfort, and numbing cream can be applied if needed.
Initial improvements in hydration and radiance can be seen within a few days, but the full benefits - such as firmer, more elastic skin - develop over several weeks as collagen production is stimulated.
Results continue to improve over three to six months after treatment. A full course of three sessions delivers the best results, with maintenance treatments recommended every six months to sustain long-term skin quality improvements.
There is minimal downtime, with most patients experiencing only mild redness or swelling for a few hours after treatment. You can return to normal activities immediately.
Yes. Polynucleotide therapy is one of the best treatments for under-eye rejuvenation, helping to reduce dark circles, fine lines, and thinning skin in this delicate area.
Polynucleotide therapy is ideal for anyone looking to improve skin quality, restore hydration, and stimulate long-term collagen production. It’s particularly beneficial for those with ageing, dull, dehydrated, or fragile skin, as well as those wanting a preventative approach to maintaining youthful skin.