Polynucleotide Treatments
IN BELSIZE PARK, HAMPSTEAD, PRIMROSE HILL AND ST JOHN’S WOOD, NORTH WEST LONDON
Ageing isn’t just about wrinkles or sagging skin - it’s a cellular process that affects the skin’s ability to regenerate, repair, and maintain hydration. Over time, collagen and elastin production slows down, skin becomes thinner, and its ability to retain moisture diminishes. This results in dullness, fine lines, loss of elasticity, and overall skin fatigue.
Unlike fillers that simply add volume, polynucleotides work at a deeper level, stimulating skin repair, improving elasticity, and enhancing overall skin health. At our Belsize Park clinic in North West London, we offer advanced polynucleotide treatments designed to restore vitality, strengthen the skin’s foundation, and support long-term regeneration for a naturally refreshed appearance.
What are Polynucleotides?
Polynucleotides are powerful biostimulators derived from DNA molecules. These natural molecules work by repairing damaged skin cells, boosting collagen production, and improving tissue quality. Unlike fillers, which add volume, polynucleotides focus on rejuvenating the skin from within, making them ideal for skin quality improvement, deep hydration, and long-term regeneration.
What to expect from treatment
Treatment begins with a consultation to assess your skin condition, goals and suitability for NCTF. We will talk through what to expect and create a personalised plan based on your skin’s needs.
The procedure itself takes around 30 minutes. Using a very fine needle or a mesotherapy technique, NCTF is placed just beneath the skin’s surface in tiny microinjections across the treatment area. The process is quick and well-tolerated, though you may feel light pinching or tingling as the solution is applied.
There may be some mild redness or small marks immediately after treatment, which usually settle within 24 to 48 hours. You can return to normal activities the same day.
For best results, a course of three to five sessions spaced two to three weeks apart is recommended, followed by maintenance every few months depending on your skin goals.
How Polynucleotides work
Polynucleotides work at a cellular level to improve the skin’s regenerative capacity. When injected into the skin, they stimulate fibroblast activity, which encourages new collagen and elastin production. This results in firmer, more hydrated skin with better texture and elasticity over time.
Unlike other treatments, polynucleotides also have anti-inflammatory properties, helping to repair damaged or stressed skin, making them particularly beneficial for those with sensitive, fragile, or ageing skin.
While immediate hydration and glow can be noticed within days, the real results develop over several weeks as the skin repairs itself from within. The treatment is performed over a series of sessions, with results improving progressively.
Combining NCTF for enhanced results
NCTF is highly versatile and often used in combination with other regenerative treatments to maximise results.
It forms the foundation of Dr Marc’s signature regenerative cocktail, where it is combined with Polynucleotides for a powerful pro-healing and collagen-stimulating boost. This pairing supports cellular renewal, improves elasticity and leaves the skin visibly stronger, healthier and more luminous. You can explore this treatment on the Polynucleotides page.
NCTF can also be combined with Botox in a microdosed technique, sometimes referred to as Mesotox or Microtox. This advanced approach smooths fine lines, minimises pores and helps create a refined, glowing finish often referred to as glass skin. This treatment is especially popular before events or for those wanting a smooth, radiant complexion without heaviness or obvious change.
At Dr Marc Aesthetics, we take a holistic, full-face approach to rejuvenation.
Get in Touch
We are always on hand to answer any questions you may have about our treatments.
Combining NCTF for enhanced results
NCTF is highly versatile and often used in combination with other regenerative treatments to maximise results.
It forms the foundation of Dr Marc’s signature regenerative cocktail, where it is combined with Polynucleotides for a powerful pro-healing and collagen-stimulating boost. This pairing supports cellular renewal, improves elasticity and leaves the skin visibly stronger, healthier and more luminous. You can explore this treatment on the Polynucleotides page.
NCTF can also be combined with Botox in a microdosed technique, sometimes referred to as Mesotox or Microtox. This advanced approach smooths fine lines, minimises pores and helps create a refined, glowing finish often referred to as glass skin. This treatment is especially popular before events or for those wanting a smooth, radiant complexion without heaviness or obvious change.
Book a consultation
If you’re considering polynucleotide treatments in Belsize Park, Hamstead, Primrose Hill and St John's Wood, North West London, we offer expert-led, personalised skin rejuvenation treatments that focus on deep regeneration, hydration, and long-term skin health. Our approach ensures that your skin not only looks better but also functions at its best, creating stronger, firmer, and more radiant skin over time.
Book a consultation today to discover how polynucleotides can help you achieve healthier, more youthful skin with natural, long-lasting results.
Frequently Asked Questions
Unlike fillers, which add volume to specific areas, polynucleotides work at a cellular level to improve overall skin quality. They stimulate collagen, improve elasticity, and enhance hydration, making the skin look naturally healthier rather than simply plumper.
Most patients experience minimal discomfort, as the injections are very fine. Polynucleotides contain natural hydrating properties that improve skin comfort, and numbing cream can be applied if needed.
Initial improvements in hydration and radiance can be seen within a few days, but the full benefits - such as firmer, more elastic skin - develop over several weeks as collagen production is stimulated.
Results continue to improve over three to six months after treatment. A full course of three sessions delivers the best results, with maintenance treatments recommended every six months to sustain long-term skin quality improvements.
There is minimal downtime, with most patients experiencing only mild redness or swelling for a few hours after treatment. You can return to normal activities immediately.
Yes. Polynucleotide therapy is one of the best treatments for under-eye rejuvenation, helping to reduce dark circles, fine lines, and thinning skin in this delicate area.
Polynucleotide therapy is ideal for anyone looking to improve skin quality, restore hydration, and stimulate long-term collagen production. It’s particularly beneficial for those with ageing, dull, dehydrated, or fragile skin, as well as those wanting a preventative approach to maintaining youthful skin.